ClinVar Miner

Submissions for variant NM_000546.6(TP53):c.96+15_96+31delinsC

dbSNP: rs1064795134
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000484030 SCV000570638 likely benign not specified 2016-06-08 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Diagnostics, LLC DBA Color Health RCV001181301 SCV001346413 likely benign Hereditary cancer-predisposing syndrome 2017-12-05 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV001181301 SCV002582299 likely benign Hereditary cancer-predisposing syndrome 2022-06-18 criteria provided, single submitter clinical testing
Genome-Nilou Lab RCV002289638 SCV002582961 likely benign Li-Fraumeni syndrome 1 2022-06-18 criteria provided, single submitter clinical testing

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