ClinVar Miner

Submissions for variant NM_000628.5(IL10RB):c.49+8G>T

gnomAD frequency: 0.00008  dbSNP: rs889875247
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001436881 SCV001639726 likely benign Inflammatory bowel disease 25 2024-10-17 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003965840 SCV004788732 likely benign IL10RB-related disorder 2020-03-09 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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