Submissions for variant NM_000719.7(CACNA1C):c.846C>T (p.Tyr282=) (rs200847105)

Minimum review status:		Collection method:
Minimum conflict level:
		ClinVar version:

Total submissions: 4

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Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
GeneDx	RCV000124069	SCV000167478	likely benign	not specified	2017-12-27	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Illumina Clinical Services Laboratory,Illumina	RCV000310705	SCV000377770	likely benign	Timothy syndrome	2016-06-14	criteria provided, single submitter	clinical testing
Illumina Clinical Services Laboratory,Illumina	RCV000365427	SCV000377771	likely benign	Brugada syndrome	2016-06-14	criteria provided, single submitter	clinical testing
Invitae	RCV000460955	SCV000562914	likely benign	Long QT syndrome	2017-12-19	criteria provided, single submitter	clinical testing

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