Submissions for variant NM_000754.4(COMT):c.472G>A (p.Val158Met)

gnomAD frequency: 0.44044  dbSNP: rs4680

Total submissions: 9

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
PreventionGenetics, part of Exact Sciences	RCV000244083	SCV000305505	benign	not specified		criteria provided, single submitter	clinical testing
Center for Forensic Mental Health, Chiba University	RCV003633481	SCV004543740	benign	Schizophrenia		criteria provided, single submitter	case-control
Breakthrough Genomics, Breakthrough Genomics	RCV004711998	SCV005275351	benign	not provided		criteria provided, single submitter	not provided
OMIM	RCV000019156	SCV000039444	benign	CATECHOL-O-METHYLTRANSFERASE POLYMORPHISM	2011-01-01	no assertion criteria provided	literature only
Bruce Budowle Laboratory, University of North Texas Health Science Center	RCV001028880	SCV001191666	drug response	Tramadol response	2018-04-28	no assertion criteria provided	research
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen	RCV000244083	SCV001743194	benign	not specified		no assertion criteria provided	clinical testing
Genome Diagnostics Laboratory, Amsterdam University Medical Center	RCV000244083	SCV001809012	benign	not specified		no assertion criteria provided	clinical testing
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+	RCV000244083	SCV001955267	benign	not specified		no assertion criteria provided	clinical testing
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	RCV000244083	SCV001970895	benign	not specified		no assertion criteria provided	clinical testing