ClinVar Miner

Submissions for variant NM_000834.4(GRIN2B):c.1341C>T (p.Asp447=) (rs35025065)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Genetic Services Laboratory, University of Chicago RCV000117189 SCV000151353 benign not specified 2014-03-17 criteria provided, single submitter clinical testing
GeneDx RCV000117189 SCV000168773 benign not specified 2014-02-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000084731 SCV000562284 benign not provided 2019-03-04 criteria provided, single submitter clinical testing
Athena Diagnostics Inc RCV000117189 SCV000613552 benign not specified 2017-06-22 criteria provided, single submitter clinical testing
Ambry Genetics RCV000716074 SCV000846907 benign History of neurodevelopmental disorder 2016-02-24 criteria provided, single submitter clinical testing
Psychiatry Genetics Yale University RCV000084731 SCV000116867 not provided not provided no assertion provided not provided

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