Submissions for variant NM_000843.4(GRM6):c.1875C>T (p.Tyr625=)

gnomAD frequency: 0.00277  dbSNP: rs62638215

Total submissions: 7

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Eurofins Ntd Llc (ga)	RCV000079325	SCV000111195	benign	not specified	2013-10-02	criteria provided, single submitter	clinical testing
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	RCV000625248	SCV000744311	likely benign	Congenital stationary night blindness 1B	2017-06-28	criteria provided, single submitter	clinical testing
Labcorp Genetics (formerly Invitae), Labcorp	RCV000086037	SCV001115914	benign	not provided	2024-01-25	criteria provided, single submitter	clinical testing
Breakthrough Genomics, Breakthrough Genomics	RCV000086037	SCV005222604	likely benign	not provided		criteria provided, single submitter	not provided
Retina International	RCV000086037	SCV000118180	not provided	not provided		no assertion provided	not provided
Clinical Genetics, Academic Medical Center	RCV000079325	SCV001917094	benign	not specified		no assertion criteria provided	clinical testing
PreventionGenetics, part of Exact Sciences	RCV003915057	SCV004728955	benign	GRM6-related disorder	2019-07-08	no assertion criteria provided	clinical testing	This variant is classified as benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).