ClinVar Miner

Submissions for variant NM_000964.4(RARA):c.826C>T (p.Arg276Trp)

dbSNP: rs786205678
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Center for Advanced Molecular Diagnostics, Cytogenetics Laboratory, Brigham and Women's Hospital RCV000171542 SCV000222915 drug response Tretinoin response 2015-03-01 no assertion criteria provided clinical testing Associated with resistance of acute promyelocytic leukemia to all trans retinoic acid (ATRA)
OMIM RCV001281697 SCV001469089 uncertain significance not provided 2021-01-14 no assertion criteria provided literature only

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