Submissions for variant NM_001039141.3(TRIOBP):c.391G>A (p.Gly131Ser)

gnomAD frequency: 0.00455  dbSNP: rs144634857

Total submissions: 8

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine	RCV000036817	SCV000060472	benign	not specified	2012-04-30	criteria provided, single submitter	clinical testing	Gly131Ser in Exon 05 of TRIOBP: This variant is not expected to have clinical si gnificance because it has been identified in 0.7% (47/6930) of European American chromosomes from a broad population by the NHLBI Exome Sequencing Project (http ://evs.gs.washington.edu/EVS; dbSNP rs144634857).
Eurofins Ntd Llc (ga)	RCV000036817	SCV000230982	likely benign	not specified	2015-03-31	criteria provided, single submitter	clinical testing
PreventionGenetics, part of Exact Sciences	RCV000036817	SCV000306101	likely benign	not specified	2016-03-01	criteria provided, single submitter	clinical testing
GeneDx	RCV000713875	SCV000732317	benign	not provided	2019-06-20	criteria provided, single submitter	clinical testing
Athena Diagnostics	RCV000713875	SCV000844515	benign	not provided	2018-07-31	criteria provided, single submitter	clinical testing
Labcorp Genetics (formerly Invitae), Labcorp	RCV000713875	SCV001102319	benign	not provided	2024-01-15	criteria provided, single submitter	clinical testing
CeGaT Center for Human Genetics Tuebingen	RCV000713875	SCV004147849	likely benign	not provided	2024-06-01	criteria provided, single submitter	clinical testing	TRIOBP: BP4, BS2
Breakthrough Genomics, Breakthrough Genomics	RCV000713875	SCV005206418	likely benign	not provided		criteria provided, single submitter	not provided