ClinVar Miner

Submissions for variant NM_001039141.3(TRIOBP):c.4178C>T (p.Pro1393Leu)

gnomAD frequency: 0.00750  dbSNP: rs28450766
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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000036823 SCV000060478 benign not specified 2012-04-30 criteria provided, single submitter clinical testing Pro1393Leu in Exon 09 of TRIOBP: This variant is not expected to have clinical s ignificance because it has been identified in 1.7% (53/3054) of African American chromosomes from a broad population by the NHLBI Exome Sequencing Project (http ://evs.gs.washington.edu/EVS; dbSNP rs28450766).
PreventionGenetics, part of Exact Sciences RCV000036823 SCV000306106 benign not specified criteria provided, single submitter clinical testing
Eurofins Ntd Llc (ga) RCV000036823 SCV000333401 benign not specified 2015-07-22 criteria provided, single submitter clinical testing
GeneDx RCV000840103 SCV000982019 benign not provided 2019-05-16 criteria provided, single submitter clinical testing
Invitae RCV000840103 SCV001031889 benign not provided 2024-01-18 criteria provided, single submitter clinical testing

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