Submissions for variant NM_001048174.2(MUTYH):c.606+21C>A

dbSNP: rs148552450

Total submissions: 8

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Mendelics	RCV000986304	SCV001135261	benign	Familial adenomatous polyposis 2	2019-05-28	criteria provided, single submitter	clinical testing
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	RCV001000429	SCV001157243	benign	not specified	2018-09-23	criteria provided, single submitter	clinical testing
Labcorp Genetics (formerly Invitae), Labcorp	RCV000986304	SCV001718973	benign	Familial adenomatous polyposis 2	2023-08-10	criteria provided, single submitter	clinical testing
GeneDx	RCV001538427	SCV001756077	likely benign	not provided	2018-06-21	criteria provided, single submitter	clinical testing	This variant is associated with the following publications: (PMID: 27829682)
Sema4, Sema4	RCV002258082	SCV002532316	benign	Hereditary cancer-predisposing syndrome	2020-08-21	criteria provided, single submitter	curation
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital	RCV001000429	SCV002552512	likely benign	not specified	2023-08-15	criteria provided, single submitter	clinical testing
Fulgent Genetics, Fulgent Genetics	RCV002503144	SCV002809042	likely benign	Familial adenomatous polyposis 2; Gastric cancer	2021-11-15	criteria provided, single submitter	clinical testing
CeGaT Center for Human Genetics Tuebingen	RCV001538427	SCV003916456	likely benign	not provided	2024-11-01	criteria provided, single submitter	clinical testing	MUTYH: BS2