ClinVar Miner

Submissions for variant NM_001048174.2(MUTYH):c.777C>T (p.Ala259=)

dbSNP: rs1057522708
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000438134 SCV000529054 likely benign not specified 2016-06-20 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Labcorp Genetics (formerly Invitae), Labcorp RCV002059737 SCV002438424 likely benign Familial adenomatous polyposis 2 2022-12-21 criteria provided, single submitter clinical testing

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