ClinVar Miner

Submissions for variant NM_001083961.2(WDR62):c.2281C>T (p.His761Tyr) (rs61744321)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000147932 SCV000169809 benign not specified 2014-01-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genetic Services Laboratory, University of Chicago RCV000147932 SCV000195425 benign not specified 2013-08-01 criteria provided, single submitter clinical testing
Illumina Clinical Services Laboratory,Illumina RCV000372973 SCV000411644 uncertain significance Primary Microcephaly 2 With or Without Cortical Malformations 2016-06-14 criteria provided, single submitter clinical testing
Invitae RCV000957950 SCV001104773 benign not provided 2019-03-05 criteria provided, single submitter clinical testing
Athena Diagnostics Inc RCV000957950 SCV001146642 benign not provided 2019-06-24 criteria provided, single submitter clinical testing

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