Submissions for variant NM_001105206.3(LAMA4):c.1710T>C (p.Ser570=)

gnomAD frequency: 0.08618  dbSNP: rs3752577

Total submissions: 6

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine	RCV000037339	SCV000060996	benign	not specified	2011-09-16	criteria provided, single submitter	clinical testing
GeneDx	RCV000037339	SCV000170059	benign	not specified	2013-11-20	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
PreventionGenetics, part of Exact Sciences	RCV000037339	SCV000308782	benign	not specified		criteria provided, single submitter	clinical testing
Invitae	RCV001521082	SCV001730342	benign	Dilated cardiomyopathy 1JJ	2024-01-31	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV001521082	SCV001981265	benign	Dilated cardiomyopathy 1JJ	2021-08-19	criteria provided, single submitter	clinical testing
Women's Health and Genetics/Laboratory Corporation of America, LabCorp	RCV000037339	SCV003929139	benign	not specified	2023-04-09	criteria provided, single submitter	clinical testing