ClinVar Miner

Submissions for variant NM_001105206.3(LAMA4):c.422+20G>T

gnomAD frequency: 0.00271  dbSNP: rs188820838
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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000199984 SCV000250515 benign not specified 2014-08-28 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV002054303 SCV002431600 benign Dilated cardiomyopathy 1JJ 2024-01-05 criteria provided, single submitter clinical testing
Fulgent Genetics, Fulgent Genetics RCV002054303 SCV002810178 likely benign Dilated cardiomyopathy 1JJ 2021-08-11 criteria provided, single submitter clinical testing
Women's Health and Genetics/Laboratory Corporation of America, LabCorp RCV000199984 SCV004029195 benign not specified 2023-07-30 criteria provided, single submitter clinical testing
Clinical Genetics, Academic Medical Center RCV000199984 SCV001918269 benign not specified no assertion criteria provided clinical testing
Genome Diagnostics Laboratory, University Medical Center Utrecht RCV000199984 SCV001932238 benign not specified no assertion criteria provided clinical testing

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