ClinVar Miner

Submissions for variant NM_001128425.1(MUTYH):c.1431G>C (p.Thr477=) (rs74318065)

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Total submissions: 10
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000162570 SCV000212986 benign Hereditary cancer-predisposing syndrome 2014-12-17 criteria provided, single submitter clinical testing
Color RCV000162570 SCV000685576 benign Hereditary cancer-predisposing syndrome 2016-03-21 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000174706 SCV000592717 uncertain significance not specified 2014-04-16 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000174706 SCV000226060 benign not specified 2014-08-21 criteria provided, single submitter clinical testing
Invitae RCV000456390 SCV000557584 benign MYH-associated polyposis 2018-01-09 criteria provided, single submitter clinical testing
Laboratory for Molecular Medicine,Partners HealthCare Personalized Medicine RCV000174706 SCV000539813 benign not specified 2016-03-29 criteria provided, single submitter clinical testing Variant identified in a genome or exome case(s) and assessed due to predicted null impact of the variant or pathogenic assertions in the literature or databases. Disclaimer: This variant has not undergone full assessment. The following are preliminary notes: Silent, high frequency
PreventionGenetics RCV000174706 SCV000806343 benign not specified 2016-03-21 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000174706 SCV000601633 benign not specified 2016-08-25 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000759880 SCV000889520 benign not provided 2016-08-25 criteria provided, single submitter clinical testing
True Health Diagnostics RCV000162570 SCV000788064 likely benign Hereditary cancer-predisposing syndrome 2017-06-21 no assertion criteria provided clinical testing

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