ClinVar Miner

Submissions for variant NM_001128425.1(MUTYH):c.505-4A>G (rs201678305)

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Total submissions: 11
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000129020 SCV000172921 benign Hereditary cancer-predisposing syndrome 2014-07-25 criteria provided, single submitter clinical testing
Color RCV000129020 SCV000685638 benign Hereditary cancer-predisposing syndrome 2016-03-21 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000212701 SCV000592685 likely benign not specified 2017-10-25 criteria provided, single submitter clinical testing
GeneDx RCV000212701 SCV000170424 benign not specified 2014-02-05 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Illumina Clinical Services Laboratory,Illumina RCV000196799 SCV000357902 uncertain significance MYH-associated polyposis 2016-06-14 criteria provided, single submitter clinical testing
Institute for Biomarker Research,Medical Diagnostic Laboratories, L.L.C. RCV000129020 SCV000576450 likely benign Hereditary cancer-predisposing syndrome 2017-02-14 criteria provided, single submitter clinical testing
Invitae RCV000196799 SCV000252749 benign MYH-associated polyposis 2018-01-25 criteria provided, single submitter clinical testing
PreventionGenetics RCV000212701 SCV000806360 benign not specified 2017-05-05 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000212701 SCV000601650 likely benign not specified 2016-12-02 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000759163 SCV000888318 likely benign not provided 2017-12-08 criteria provided, single submitter clinical testing
True Health Diagnostics RCV000129020 SCV000788069 likely benign Hereditary cancer-predisposing syndrome 2017-09-29 no assertion criteria provided clinical testing

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