Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Wangler Lab, |
RCV002286328 | SCV002574699 | uncertain significance | Primary dilated cardiomyopathy | criteria provided, single submitter | clinical testing | This indel variant in MYH14 results in (p.Glu330Leu).This change was seen on exome through the Texome Project (R01HG011795). It is predicted to be deleterious and is highly conserved (PP3). This change is not seen on population databases of healthy individuals (PM2). We classify this variant to have uncertain significance. |