ClinVar Miner

Submissions for variant NM_001166108.2(PALLD):c.1965-12574C>T

gnomAD frequency: 0.00004  dbSNP: rs763225090
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001413428 SCV001615542 likely benign Pancreatic adenocarcinoma 2023-10-04 criteria provided, single submitter clinical testing
Ambry Genetics RCV004038105 SCV003737681 uncertain significance not specified 2022-06-28 criteria provided, single submitter clinical testing The c.457C>T (p.P153S) alteration is located in exon 2 (coding exon 1) of the PALLD gene. This alteration results from a C to T substitution at nucleotide position 457, causing the proline (P) at amino acid position 153 to be replaced by a serine (S). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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