ClinVar Miner

Submissions for variant NM_001166108.2(PALLD):c.2625C>T (p.Gly875=)

dbSNP: rs2151407453
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001412747 SCV001614844 likely benign Pancreatic adenocarcinoma 2019-03-06 criteria provided, single submitter clinical testing
Ambry Genetics RCV004038096 SCV002740315 likely benign not specified 2022-10-11 criteria provided, single submitter clinical testing This alteration is classified as likely benign based on a combination of the following: seen in unaffected individuals, population frequency, intact protein function, lack of segregation with disease, co-occurrence, RNA analysis, in silico models, amino acid conservation, lack of disease association in case-control studies, and/or the mechanism of disease or impacted region is inconsistent with a known cause of pathogenicity.

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