ClinVar Miner

Submissions for variant NM_001199085.3(TDRD5):c.2630G>T (p.Gly877Val)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004872042 SCV005518326 uncertain significance not specified 2024-11-24 criteria provided, single submitter clinical testing The c.2630G>T (p.G877V) alteration is located in exon 16 (coding exon 15) of the TDRD5 gene. This alteration results from a G to T substitution at nucleotide position 2630, causing the glycine (G) at amino acid position 877 to be replaced by a valine (V). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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