Submissions for variant NM_001276345.2(TNNT2):c.53-11_53-7del

dbSNP: rs45533739

Total submissions: 21

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine	RCV000036600	SCV000060255	benign	not specified	2006-11-07	criteria provided, single submitter	clinical testing
GeneDx	RCV000036600	SCV000209214	benign	not specified	2013-09-25	criteria provided, single submitter	clinical testing	This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Eurofins Ntd Llc (ga)	RCV000036600	SCV000230138	benign	not specified	2015-01-12	criteria provided, single submitter	clinical testing
PreventionGenetics, part of Exact Sciences	RCV000036600	SCV000305598	benign	not specified		criteria provided, single submitter	clinical testing
Illumina Laboratory Services, Illumina	RCV000330905	SCV000353368	likely benign	Left ventricular noncompaction cardiomyopathy	2016-06-14	criteria provided, single submitter	clinical testing
Illumina Laboratory Services, Illumina	RCV000385533	SCV000353369	likely benign	Familial restrictive cardiomyopathy	2016-06-14	criteria provided, single submitter	clinical testing
Illumina Laboratory Services, Illumina	RCV000291224	SCV000353370	likely benign	Dilated Cardiomyopathy, Dominant	2016-06-14	criteria provided, single submitter	clinical testing
Illumina Laboratory Services, Illumina	RCV000327238	SCV000353371	likely benign	Hypertrophic cardiomyopathy	2016-06-14	criteria provided, single submitter	clinical testing
Invitae	RCV000646080	SCV000767837	benign	Hypertrophic cardiomyopathy 2; Dilated cardiomyopathy 1D; Cardiomyopathy, familial restrictive, 3	2024-02-01	criteria provided, single submitter	clinical testing
Color Diagnostics, LLC DBA Color Health	RCV000775982	SCV000910503	benign	Cardiomyopathy	2018-03-09	criteria provided, single submitter	clinical testing
Mendelics	RCV000986505	SCV001135518	benign	Hypertrophic cardiomyopathy 2	2019-05-28	criteria provided, single submitter	clinical testing
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	RCV001811245	SCV001158897	benign	not provided	2023-11-29	criteria provided, single submitter	clinical testing
CHEO Genetics Diagnostic Laboratory, Children's Hospital of Eastern Ontario	RCV000775982	SCV001333864	benign	Cardiomyopathy	2019-04-03	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV001838532	SCV002098610	benign	Dilated cardiomyopathy 1D	2021-09-10	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV001838533	SCV002098611	benign	Cardiomyopathy, familial restrictive, 3	2021-09-10	criteria provided, single submitter	clinical testing
Genome-Nilou Lab	RCV000986505	SCV002098612	benign	Hypertrophic cardiomyopathy 2	2021-09-10	criteria provided, single submitter	clinical testing
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen	RCV000036600	SCV001740498	benign	not specified		no assertion criteria provided	clinical testing
Genome Diagnostics Laboratory, University Medical Center Utrecht	RCV000036600	SCV001932432	benign	not specified		no assertion criteria provided	clinical testing
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+	RCV000036600	SCV001958870	benign	not specified		no assertion criteria provided	clinical testing
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center	RCV000036600	SCV001967097	benign	not specified		no assertion criteria provided	clinical testing
Cohesion Phenomics	RCV000775982	SCV003803066	benign	Cardiomyopathy	2022-10-10	no assertion criteria provided	clinical testing