ClinVar Miner

Submissions for variant NM_001278064.2(GRM1):c.2785G>A (p.Val929Ile)

gnomAD frequency: 0.01171  dbSNP: rs2941
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 5
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Athena Diagnostics RCV001288990 SCV001476467 benign not specified 2023-12-13 criteria provided, single submitter clinical testing
GeneDx RCV001776170 SCV002013274 likely benign not provided 2024-04-27 criteria provided, single submitter clinical testing See Variant Classification Assertion Criteria.
Labcorp Genetics (formerly Invitae), Labcorp RCV001776170 SCV003239836 benign not provided 2025-02-03 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV001776170 SCV005227813 likely benign not provided criteria provided, single submitter not provided
PreventionGenetics, part of Exact Sciences RCV003973188 SCV004789161 benign GRM1-related disorder 2019-09-06 no assertion criteria provided clinical testing This variant is classified as benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.