ClinVar Miner

Submissions for variant NM_001287491.2(TET3):c.1371C>T (p.Pro457=)

gnomAD frequency: 0.01009  dbSNP: rs61742889
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV001707272 SCV001935426 benign not provided 2020-10-15 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV001707272 SCV005242970 benign not provided criteria provided, single submitter not provided
PreventionGenetics, part of Exact Sciences RCV004551984 SCV004787777 benign TET3-related disorder 2023-07-09 no assertion criteria provided clinical testing This variant is classified as benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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