Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Ambry Genetics | RCV004503851 | SCV005006150 | uncertain significance | not specified | 2023-12-20 | criteria provided, single submitter | clinical testing | The c.2296T>G (p.F766V) alteration is located in exon 17 (coding exon 16) of the PIK3C2G gene. This alteration results from a T to G substitution at nucleotide position 2296, causing the phenylalanine (F) at amino acid position 766 to be replaced by a valine (V). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear. |