ClinVar Miner

Submissions for variant NM_001288772.2(PIK3C2G):c.2674C>T (p.His892Tyr)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV005389390 SCV006045602 uncertain significance not specified 2024-12-24 criteria provided, single submitter clinical testing The c.2551C>T (p.H851Y) alteration is located in exon 18 (coding exon 17) of the PIK3C2G gene. This alteration results from a C to T substitution at nucleotide position 2551, causing the histidine (H) at amino acid position 851 to be replaced by a tyrosine (Y). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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