Total submissions: 2
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Ambry Genetics | RCV004099401 | SCV003569302 | uncertain significance | not specified | 2021-08-02 | criteria provided, single submitter | clinical testing | The c.1564T>A (p.Y522N) alteration is located in exon 15 (coding exon 15) of the ATP11C gene. This alteration results from a T to A substitution at nucleotide position 1564, causing the tyrosine (Y) at amino acid position 522 to be replaced by an asparagine (N). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear. |
Revvity Omics, |
RCV003492810 | SCV004234549 | uncertain significance | X-linked congenital hemolytic anemia | 2023-05-03 | criteria provided, single submitter | clinical testing |