ClinVar Miner

Submissions for variant NM_001457.4(FLNB):c.4222+19A>C

gnomAD frequency: 0.00319  dbSNP: rs146229370
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000603220 SCV000726442 likely benign not specified 2018-01-03 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Labcorp Genetics (formerly Invitae), Labcorp RCV002064254 SCV002404518 benign not provided 2025-01-27 criteria provided, single submitter clinical testing
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories RCV002064254 SCV004562925 benign not provided 2023-07-27 criteria provided, single submitter clinical testing

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