ClinVar Miner

Submissions for variant NM_001458.4(FLNC):c.4301G>T (p.Arg1434Leu) (rs143623535)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000498731 SCV000590478 likely benign not provided 2020-09-02 criteria provided, single submitter clinical testing Has not been previously published as pathogenic or benign to our knowledge; Reported in ClinVar (ClinVar Variant ID# 432723; Landrum et al., 2016)
Invitae RCV001086180 SCV000771029 likely benign Myofibrillar myopathy, filamin C-related; Myopathy, distal, 4; Cardiomyopathy, familial hypertrophic, 26; Dilated Cardiomyopathy, Dominant 2020-10-08 criteria provided, single submitter clinical testing

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