ClinVar Miner

Submissions for variant NM_001558.4(IL10RA):c.181C>G (p.Leu61Val)

gnomAD frequency: 0.01376  dbSNP: rs4252250
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Illumina Laboratory Services, Illumina RCV000541829 SCV000367421 likely benign Inflammatory bowel disease 28 2017-04-27 criteria provided, single submitter clinical testing This variant was observed as part of a predisposition screen in an ostensibly healthy population. A literature search was performed for the gene, cDNA change, and amino acid change (where applicable). No publications were found based on this search. Allele frequency data from public databases allowed determination this variant is unlikely to cause disease. Therefore, this variant is classified as likely benign.
Invitae RCV000541829 SCV000648401 benign Inflammatory bowel disease 28 2024-01-30 criteria provided, single submitter clinical testing

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