Total submissions: 3
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Labcorp Genetics |
RCV002166298 | SCV002479660 | likely benign | not provided | 2025-01-06 | criteria provided, single submitter | clinical testing | |
Fulgent Genetics, |
RCV002500350 | SCV002806517 | likely benign | Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome; Brain small vessel disease 1 with or without ocular anomalies; Hemorrhage, intracerebral, susceptibility to; Retinal arterial tortuosity; Microangiopathy and leukoencephalopathy, pontine, autosomal dominant | 2021-08-12 | criteria provided, single submitter | clinical testing | |
Prevention |
RCV004741253 | SCV005362671 | likely benign | COL4A1-related disorder | 2024-08-03 | no assertion criteria provided | clinical testing | This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications). |