Total submissions: 4
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Labcorp Genetics |
RCV001878497 | SCV002127246 | benign | not provided | 2025-01-29 | criteria provided, single submitter | clinical testing | |
Fulgent Genetics, |
RCV002478131 | SCV002788938 | uncertain significance | Intervertebral disc disorder; Marshall syndrome; Stickler syndrome type 2; Fibrochondrogenesis 1; Hearing loss, autosomal dominant 37 | 2022-03-09 | criteria provided, single submitter | clinical testing | |
Gene |
RCV001878497 | SCV004030524 | uncertain significance | not provided | 2023-02-24 | criteria provided, single submitter | clinical testing | Reported in a patient with retinitis pigmentosa in published literature (Comander et al., 2017); In silico analysis supports that this missense variant has a deleterious effect on protein structure/function; This variant is associated with the following publications: (PMID: 28981474) |
Laboratory of Prof. |
RCV004584929 | SCV005073739 | likely pathogenic | Hearing loss, autosomal dominant 37 | 2024-05-02 | criteria provided, single submitter | research | Likely pathogenic by Deafness Variation Database based on PMID:28981474 |