ClinVar Miner

Submissions for variant NM_001904.4(CTNNB1):c.121A>G (p.Thr41Ala) (rs121913412)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 13
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Database of Curated Mutations (DoCM) RCV000419429 SCV000506033 likely pathogenic Adenocarcinoma of prostate 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000430146 SCV000506034 likely pathogenic Malignant melanoma of skin 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000440817 SCV000506035 likely pathogenic Neoplasm of the large intestine 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000421675 SCV000506036 likely pathogenic Pancreatic adenocarcinoma 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000431914 SCV000506037 likely pathogenic Malignant neoplasm of body of uterus 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000438649 SCV000506038 likely pathogenic Hepatocellular carcinoma 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000421001 SCV000506039 likely pathogenic Adrenocortical carcinoma 2016-05-31 no assertion criteria provided literature only
Database of Curated Mutations (DoCM) RCV000432978 SCV000506040 likely pathogenic Lung adenocarcinoma 2016-05-31 no assertion criteria provided literature only
Donald Williams Parsons Laboratory,Baylor College of Medicine RCV000019142 SCV000599916 other Hepatoblastoma 2016-05-01 no assertion criteria provided clinical testing
OMIM RCV000019142 SCV000039430 pathogenic Hepatoblastoma 1999-09-01 no assertion criteria provided literature only
OMIM RCV000019143 SCV000039431 pathogenic Desmoid tumor, somatic 1999-09-01 no assertion criteria provided literature only
Richard Lifton Laboratory, Yale University School of Medicine RCV000087196 SCV000120058 unknown not provided no assertion criteria provided not provided Converted during submission to Uncertain significance.
Richard Lifton Laboratory, Yale University School of Medicine RCV000087196 SCV000155161 probable-pathogenic not provided no assertion criteria provided not provided Converted during submission to Likely pathogenic.

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.