ClinVar Miner

Submissions for variant NM_002019.4(FLT1):c.2838G>T (p.Glu946Asp)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV005327947 SCV006005020 uncertain significance not specified 2025-01-27 criteria provided, single submitter clinical testing The c.2838G>T (p.E946D) alteration is located in exon 21 (coding exon 21) of the FLT1 gene. This alteration results from a G to T substitution at nucleotide position 2838, causing the glutamic acid (E) at amino acid position 946 to be replaced by an aspartic acid (D). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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