ClinVar Miner

Submissions for variant NM_002087.3(GRN):c.1227G>A (p.Thr409=) (rs140298583)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
PreventionGenetics,PreventionGenetics RCV000242834 SCV000308699 likely benign not specified criteria provided, single submitter clinical testing
Athena Diagnostics Inc RCV000576303 SCV000677375 benign Grn-related frontotemporal lobar degeneration with Tdp43 inclusions 2017-06-28 criteria provided, single submitter clinical testing
Ambry Genetics RCV000715977 SCV000846810 likely benign Seizures 2016-05-19 criteria provided, single submitter clinical testing Synonymous alterations with insufficient evidence to classify as benign
Invitae RCV000876310 SCV001018868 benign Grn-related frontotemporal lobar degeneration with Tdp43 inclusions; Ceroid lipofuscinosis, neuronal, 11 2019-12-31 criteria provided, single submitter clinical testing

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