ClinVar Miner

Submissions for variant NM_002160.4(TNC):c.2129C>T (p.Thr710Met)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 2
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004473018 SCV004969640 uncertain significance not specified 2023-12-15 criteria provided, single submitter clinical testing The c.2129C>T (p.T710M) alteration is located in exon 4 (coding exon 3) of the TNC gene. This alteration results from a C to T substitution at nucleotide position 2129, causing the threonine (T) at amino acid position 710 to be replaced by a methionine (M). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.
Center for Computational Biology & Bioinformatics, University of California, San Diego RCV004573465 SCV005050001 uncertain significance Meniere disease 2024-06-03 no assertion criteria provided research

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.