ClinVar Miner

Submissions for variant NM_002447.4(MST1R):c.1861A>T (p.Lys621Ter)

gnomAD frequency: 0.00252  dbSNP: rs9819888
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV000901781 SCV001046169 benign not provided 2019-12-31 criteria provided, single submitter clinical testing
Fulgent Genetics, Fulgent Genetics RCV002505307 SCV002805126 likely benign Nasopharyngeal carcinoma, susceptibility to, 3 2021-08-06 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003968259 SCV004783003 benign MST1R-related disorder 2019-09-10 no assertion criteria provided clinical testing This variant is classified as benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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