ClinVar Miner

Submissions for variant NM_002520.6(NPM1):c.860_863dupTCTG (rs587776806)

Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 3
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Hospital of the University of Pennsylvania,Center for Personalized Diagnostics RCV000203461 SCV000258461 pathogenic Myelodysplastic syndrome progressed to acute myeloid leukemia 2016-01-08 criteria provided, single submitter clinical testing Usually associated with favorable prognosis in AML unless a concomitant FLT3-ITD mutation is also present
OMIM RCV000015035 SCV000035291 pathogenic Acute myeloid leukemia 2005-01-20 no assertion criteria provided literature only
NIHR Bioresource Rare Diseases, University of Cambridge RCV000015035 SCV001162247 pathogenic Acute myeloid leukemia no assertion criteria provided research

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.