ClinVar Miner

Submissions for variant NM_002524.5(NRAS):c.451-10C>T

dbSNP: rs1463590425
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV002082202 SCV002422454 likely benign RASopathy 2023-10-24 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003895873 SCV004712737 likely benign NRAS-related disorder 2020-08-25 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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