ClinVar Miner

Submissions for variant NM_002524.5(NRAS):c.83T>G (p.Phe28Cys)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Institute of Human Genetics, University of Goettingen RCV004821373 SCV005441775 uncertain significance Noonan syndrome 6 2025-01-02 criteria provided, single submitter clinical testing PM2_sup: extremely low in population databases PP3: For a missense or a splicing region variant, computational prediction tools unanimously support a deleterious effect on the gene

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