ClinVar Miner

Submissions for variant NM_002878.3(RAD51D):c.216C>T (p.Tyr72=) (rs148690585)

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Total submissions: 7
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000127697 SCV000214933 likely benign Hereditary cancer-predisposing syndrome 2014-08-18 criteria provided, single submitter clinical testing
Color RCV000127697 SCV000686430 likely benign Hereditary cancer-predisposing syndrome 2015-11-02 criteria provided, single submitter clinical testing
Counsyl RCV000410416 SCV000488963 likely benign Breast-ovarian cancer, familial 4 2016-07-26 criteria provided, single submitter clinical testing
GeneDx RCV000212956 SCV000171276 benign not specified 2014-02-24 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genetic Services Laboratory, University of Chicago RCV000212956 SCV000596690 likely benign not specified 2017-05-02 criteria provided, single submitter clinical testing
Invitae RCV000410416 SCV000561571 benign Breast-ovarian cancer, familial 4 2018-01-04 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000212956 SCV000602154 likely benign not specified 2016-09-28 criteria provided, single submitter clinical testing

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