ClinVar Miner

Submissions for variant NM_002878.3(RAD51D):c.666A>G (p.Glu222=) (rs114012742)

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Total submissions: 9
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000212964 SCV000211648 benign not specified 2014-08-06 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Ambry Genetics RCV000160941 SCV000213853 likely benign Hereditary cancer-predisposing syndrome 2014-07-09 criteria provided, single submitter clinical testing
Invitae RCV000206447 SCV000262143 benign Breast-ovarian cancer, familial 4 2017-12-20 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000212964 SCV000333809 likely benign not specified 2015-09-11 criteria provided, single submitter clinical testing
Counsyl RCV000206447 SCV000488960 likely benign Breast-ovarian cancer, familial 4 2016-07-26 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000212964 SCV000602164 likely benign not specified 2017-05-30 criteria provided, single submitter clinical testing
Color RCV000160941 SCV000686478 benign Hereditary cancer-predisposing syndrome 2015-10-15 criteria provided, single submitter clinical testing
PreventionGenetics,PreventionGenetics RCV000212964 SCV000806581 benign not specified 2017-06-07 criteria provided, single submitter clinical testing
True Health Diagnostics RCV000160941 SCV000788207 likely benign Hereditary cancer-predisposing syndrome 2017-09-29 no assertion criteria provided clinical testing

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