ClinVar Miner

Submissions for variant NM_002878.3(RAD51D):c.668-4G>A (rs1001440122)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000459829 SCV000561564 likely benign Breast-ovarian cancer, familial 4 2019-12-31 criteria provided, single submitter clinical testing
Ambry Genetics RCV000562382 SCV000667144 likely benign Hereditary cancer-predisposing syndrome 2019-09-27 criteria provided, single submitter clinical testing Insufficient evidence;RNA Studies
GeneDx RCV000611838 SCV000716780 likely benign not specified 2017-03-15 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color RCV000562382 SCV001346979 uncertain significance Hereditary cancer-predisposing syndrome 2019-05-22 criteria provided, single submitter clinical testing

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