ClinVar Miner

Submissions for variant NM_002878.3(RAD51D):c.873C>T (p.Arg291=) (rs140848654)

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Total submissions: 10
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories RCV000756585 SCV000884440 benign not provided 2018-01-29 criteria provided, single submitter clinical testing
Ambry Genetics RCV000127699 SCV000213971 likely benign Hereditary cancer-predisposing syndrome 2014-07-22 criteria provided, single submitter clinical testing
Color RCV000127699 SCV000686494 benign Hereditary cancer-predisposing syndrome 2015-04-22 criteria provided, single submitter clinical testing
Counsyl RCV000204704 SCV000488521 benign Breast-ovarian cancer, familial 4 2016-05-25 criteria provided, single submitter clinical testing
GeneDx RCV000212973 SCV000171278 benign not specified 2014-01-09 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Illumina Clinical Services Laboratory,Illumina RCV000324952 SCV000401965 likely benign Breast and Ovarian Cancer Susceptibility 2016-06-14 criteria provided, single submitter clinical testing
Invitae RCV000204704 SCV000262502 benign Breast-ovarian cancer, familial 4 2018-01-12 criteria provided, single submitter clinical testing
PreventionGenetics RCV000212973 SCV000806590 benign not specified 2017-08-11 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000212973 SCV000602168 likely benign not specified 2017-02-16 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000756585 SCV000888613 benign not provided 2018-04-10 criteria provided, single submitter clinical testing

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