ClinVar Miner

Submissions for variant NM_003000.3(SDHB):c.424-37TTC[10]

dbSNP: rs34261028
Minimum review status: Collection method:
Minimum conflict level:
ClinVar version:
Total submissions: 10
Download table as spreadsheet
Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Women's Health and Genetics/Laboratory Corporation of America, LabCorp RCV000030449 SCV000053118 benign Pheochromocytoma 2011-08-18 criteria provided, single submitter curation Converted during submission to Benign.
PreventionGenetics, part of Exact Sciences RCV000248855 SCV000309333 benign not specified criteria provided, single submitter clinical testing
GeneDx RCV000248855 SCV000567458 likely benign not specified 2017-08-22 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories RCV001811222 SCV002058084 benign not provided 2023-11-08 criteria provided, single submitter clinical testing
Invitae RCV002054523 SCV002400270 benign Gastrointestinal stromal tumor; Paragangliomas 4; Pheochromocytoma 2024-02-01 criteria provided, single submitter clinical testing
Sema4, Sema4 RCV002256011 SCV002527078 benign Hereditary cancer-predisposing syndrome 2021-04-04 criteria provided, single submitter curation
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital RCV000248855 SCV002552141 likely benign not specified 2023-08-15 criteria provided, single submitter clinical testing
Fulgent Genetics, Fulgent Genetics RCV002496469 SCV002806414 likely benign Gastrointestinal stromal tumor; Carney-Stratakis syndrome; Paragangliomas 4; Pheochromocytoma; Mitochondrial complex 2 deficiency, nuclear type 4 2021-11-01 criteria provided, single submitter clinical testing
CeGaT Center for Human Genetics Tuebingen RCV001811222 SCV002821007 likely benign not provided 2024-04-01 criteria provided, single submitter clinical testing SDHB: BS2
Color Diagnostics, LLC DBA Color Health RCV003514304 SCV004362274 benign Paragangliomas 4 2022-09-20 criteria provided, single submitter clinical testing

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. Neither the University of Utah nor the National Institutes of Health independently verfies the submitted information. If you have questions about the information contained on this website, please see a health care professional.