Total submissions: 1
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Division of Host Defense, |
RCV000508928 | SCV000606721 | risk factor | Virus-induced diabetes | no assertion criteria provided | reference population | rs953883300, rs2304259, rs17000730, rs17000728, rs2304258 and variant NC_000019.10:g.10381501A>T are in complete linkage disequilibriumin, the haplotype was named TYK2 Promoter Variant. The entire haplotype is the risk factor for Virus-induced type 1 diabetes in Japanese. These SNPs cause mild decrease of anti-viral response. |