ClinVar Miner

Submissions for variant NM_003667.4(LGR5):c.1067T>G (p.Val356Gly)

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Total submissions: 1
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV004642430 SCV005133244 uncertain significance not specified 2024-06-05 criteria provided, single submitter clinical testing The c.1067T>G (p.V356G) alteration is located in exon 11 (coding exon 11) of the LGR5 gene. This alteration results from a T to G substitution at nucleotide position 1067, causing the valine (V) at amino acid position 356 to be replaced by a glycine (G). Based on insufficient or conflicting evidence, the clinical significance of this alteration remains unclear.

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