ClinVar Miner

Submissions for variant NM_003672.4(CDC14A):c.1755+110C>G

gnomAD frequency: 0.00016  dbSNP: rs188557928
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine RCV000825659 SCV000967045 benign not specified 2017-08-23 criteria provided, single submitter clinical testing p.Ala622Gly in exon 15 of CDC14A: This variant is not expected to have clinical significance because it has been identified in 0.97% (83/8582) of East Asian chr omosomes by the Exome Aggregation Consortium (ExAC, http://exac.broadinstitute.o rg; dbSNP rs188557928).
Labcorp Genetics (formerly Invitae), Labcorp RCV002538224 SCV003256402 benign not provided 2024-11-03 criteria provided, single submitter clinical testing
PreventionGenetics, part of Exact Sciences RCV003948015 SCV004764218 benign CDC14A-related disorder 2019-10-07 no assertion criteria provided clinical testing This variant is classified as benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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