ClinVar Miner

Submissions for variant NM_003803.3(MYOM1):c.2879T>C (p.Ile960Thr) (rs1071600)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine RCV000214925 SCV000269356 benign not specified 2014-11-24 criteria provided, single submitter clinical testing Ile960Thr in exon 19 of MYOM1: This variant is not expected to have clinical sig nificance because it has been identified in 26.1% (1017/3904) of African America n chromosomes from a broad population by the NHLBI Exome Sequencing Project (htt p://; dbSNP rs1071600).
Ambry Genetics RCV000617580 SCV000739811 benign Cardiovascular phenotype 2019-02-07 criteria provided, single submitter clinical testing
GeneDx RCV000838128 SCV000979992 benign not provided 2018-06-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.

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