ClinVar Miner

Submissions for variant NM_003803.3(MYOM1):c.3576-5C>T (rs7232329)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine RCV000220145 SCV000269360 benign not specified 2014-11-24 criteria provided, single submitter clinical testing 3576-5C>T in intron 23 of MYOM1: This variant is not expected to have clinical s ignificance because it has been identified in 44.7% (3679/8230) of European Amer ican chromosomes from a broad population by the NHLBI Exome Sequencing Project (; dbSNP rs7232329).
Ambry Genetics RCV000620247 SCV000739801 benign Cardiovascular phenotype 2012-07-11 criteria provided, single submitter clinical testing
GeneDx RCV000837583 SCV000979439 benign not provided 2018-06-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.

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