ClinVar Miner

Submissions for variant NM_003805.5(CRADD):c.554G>A (p.Arg185Gln)

gnomAD frequency: 0.01629  dbSNP: rs73365258
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV000967283 SCV001114662 benign not provided 2024-01-15 criteria provided, single submitter clinical testing
GeneDx RCV000967283 SCV001844575 benign not provided 2021-05-04 criteria provided, single submitter clinical testing
Breakthrough Genomics, Breakthrough Genomics RCV000967283 SCV005232596 benign not provided criteria provided, single submitter not provided
PreventionGenetics, part of Exact Sciences RCV003936036 SCV004755811 likely benign CRADD-related disorder 2019-12-05 no assertion criteria provided clinical testing This variant is classified as likely benign based on ACMG/AMP sequence variant interpretation guidelines (Richards et al. 2015 PMID: 25741868, with internal and published modifications).

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